CHB Platforms / André Lwoff Institute / Paul Brousse Hospital

UMS 44 / Institut Biomédical du Val de Bièvre (IBVB) ensures research excellence at the Bicêtre and P. Brousse sites, through the pooling of human and financial resources, the dissemination of information and a collaborative dynamic between the different structures.

Cytometry Service

The flow cytometry platform is an essential service for the advancement of projects within the various units of the regional SFR federation structure at the Paul Brousse Hospital site. Researchers using this platform work in diverse fields such as embryonic stem cells, adult stem cells and their microenvironment, oncology, hematology, and hepatology.

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Cellular Imaging Service

Fluorescence optical microscopy imaging is a rapidly expanding field and has become an essential method for biological research. Recent technological advances have led to the development of faster, higher-resolution microscopes capable of capturing three-dimensional images of living biological samples. Simultaneously, significant progress has been made in the development of stable and luminous fluorescent probes, revolutionizing the ability to track individual cells in vivo.

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Biological Resources Service

The animal facility, classified A2, consists of several distinct areas: an EOPS (Specific Pathogenic Organism Free) rearing area, a "clean conventional" housing area for experimental animals, a NOD-SCID area for immunodeficient mice in an isolator, a room dedicated to the study of chronobiology and a room giving access to the IVIS system for imaging small animals.

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Platforms of the Paris-Saclay Pharmacy Faculty

Engineering and Platforms for Therapeutic Innovation (IPSIT Université-Paris-Saclay, US31 Inserm, UAR3679 CNRS) is a Joint Service Unit (UMS) that brings together 11 technological platforms and is resolutely at the interface of chemistry, biology, and clinical practice by establishing the link between the disease target and the drug. It is supported by a Federative Research Structure (SFR) that unites the UMS-IPSIT and 25 research teams.

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ANIMEX: Pet shop and functional exploration

The AnimEx platform is located on the campus of the Faculty of Pharmacy at Paris-Saclay University. Its primary mission is to provide the scientific community in the public and private sectors with animal housing and breeding facilities, as well as equipment for the functional exploration of small animals. AnimEx is a member of CAPSud (Paris South Animal Facility Consortium) and is affiliated with CEEA Ethics Committee No. 26.

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Scien-Tech Glass: scientific and technical glassware

The Verre Scien-Tech platform is located on the site of the Faculty of Pharmacy of the University of Paris-Saclay in Orsay. Its main missions are the Design, Manufacture and Repair of glass and related equipment for scientific use in research and teaching, as well as Expertise in the field of glass products.

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PHIC: Experimental Histology Platform

The Experimental Histology platform located in UMR-S996 on the Henri Moissan site in ORSAY (Paris-Saclay) and created in 2010 aims to offer its expertise in the immunopathological analysis of genetically modified mice and animal models of human inflammatory and/or hematological pathologies.

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MIPSIT: cellular imaging (confocal, videomicroscope, high-resolution STED)

This platform, open to all research teams, has as its primary mission to offer expertise and access to high-performance technological tools in the field of photon microscopy and image analysis. Visualizing the localization of molecules of interest or monitoring dynamic processes in three dimensions at the tissue, cellular, or subcellular level provides an additional methodological approach to understanding human and animal pathologies.

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CIBLOT: molecular screening

The platform is called CIBLOT, which stands for "Screening, Biology-Chemistry Interface, and Operational Transfer Laboratory" in French. CIBLOT's primary objective is to help researchers identify small molecules that can be used as probes to modulate biological functions and to provide lead molecules for drug discovery targeting various diseases. CIBLOT serves as a key interface for collaboration between biologists and chemists, and a framework for transferring scientific and technological expertise between them. Services will be available to academic and industrial researchers outside the Faculty of Pharmacy. CIBLOT will contribute to training in high-throughput screening and pharmaceutical research.

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BIOINFO: Bioinformatics and Biostatistics Processing

IPSIT Bioinfo provides bioinformatics, biostatistics and functional analysis services for omic data processing.

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SAMM: mass spectrometry

The Drug and Metabolite Analysis Service (SAMM) is a mass spectrometry instrumental platform specializing in the structural analysis and quantification of small molecules, as well as lipidomic profiling. SAMM provides researchers with mass spectrometry instruments coupled with separation techniques through service agreements or open access.

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CYM: cytometry

The Cytometry Platform offers its expertise in the context of fundamental and pre-clinical research projects on experimental models as well as clinical research protocols in humans.

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ACTAGen: transcriptomics, genomics

The ACTAGen platform offers transcriptome analysis technologies using RNA-seq or microarrays, and expression analysis of selected genes by real-time quantitative PCR and digital PCR. It also enables the analysis of genotypic variants.

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PROTEOMIC: proteomics platform

Within the network of Paris-Saclay proteomics platforms (P2S), and affiliated to the Graduate School of Health and Drug Science (GS HeaDS), PROTEOMIC - IPSIT facility is open to researchers dedicated to pharmaceutical sciences belonging to academic or private laboratories. PROTEOMIC - IPSIT collaborates with users by providing them technologies and expertise for qualitative and quantitative proteome analysis.

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